Senior / Associate Scientist, Translational
Comp: $45 - $55/hr DOE
Status: Contractor
Must be in San Diego
No Phds
The Opportunity
We're looking for a hands-on translational researcher to drive biomarker discovery and translational studies across oncology, immunology, and in vivo pharmacology programs. You'll run molecular and tissue-based assays, manage sample workflows end to end, analyze resulting data, and work closely with cross-functional research teams.
The ideal candidate brings strong experience in qPCR, tissue processing, mammalian cell culture, and biomarker analysis. Background in IHC, multiplex IHC, immunofluorescence, spatial biology, or other tissue-based techniques is a strong plus.
What You'll Do
- Lead translational research studies spanning oncology, immunology, and in vivo pharmacology
- Carry out RNA/DNA extraction, qPCR and RT-qPCR, gene-expression analysis, and sample prep
- Run mammalian cell culture and support in vitro pharmacology work
- Process and manage tissue samples for downstream molecular and histological analysis
- Perform or coordinate IHC, multiplex IHC, immunofluorescence, spatial biology, and related biomarker assays
- Support tissue-based molecular characterization using both internal platforms and external partners
- Analyze data, keep precise experimental records, and communicate results clearly
- Optimize, validate, and troubleshoot assays to strengthen quality and reproducibility
- Partner closely with Translational Sciences, Biology, Pharmacology, and Biomarker teams
- Help maintain lab compliance, inventory, equipment upkeep, and documentation
What You Bring
- Bachelor's degree in biology, molecular biology, biotechnology, immunology, cancer biology, or related field
- 8+ years of relevant biotech or pharma industry experience
- Hands-on expertise with qPCR/RT-qPCR, nucleic acid isolation, mammalian cell culture, tissue processing, and IHC
- Strong documentation habits and data-analysis skills
- Comfort independently driving lab studies in a fast-paced, cross-functional setting
Nice to Have
- Experience supporting oncology, immunology, or early clinical development programs
- Multiplex IHC, immunofluorescence, spatial biology, FFPE tissue, or digital pathology experience
- Familiarity with translational biomarker development and PD assessments
- Exposure to in vivo pharmacology and tissue-collection workflows
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